TỔNG HỢP VẬT LIỆU SILICA GEL MANG CHẤT LỎNG ION KHUNG PYRROLIDINE LÀM CỘT CHIẾT PHA RẮN TRONG PHÂN TÍCH ĐỒNG THỜI KHÁNG SINH ENROFLOXACIN, NORFLOXACIN VÀ DIFLOXACIN

Huỳnh Thị Thanh Tâm, Nguyễn Thái Thế, Nguyễn Diệu Linh, Đỗ Hoàng Ngọc Mai, Nguyễn Hồ Thùy Linh, Đoàn Lê Hoàng Tân, Trần Hoàng Phương

Tóm tắt


Chúng tôi đã phát triển một loại vật liệu mới là sử dụng chất lỏng ion mang lên silica gel làm vật liệu chiết pha rắn để phân tích fluoroquinolones. Trong nghiên cứu này, 1-methyl-1-octadecylpyrrolidinium bromide đã được tổng hợp và cố định lên silica gel (ILSPE). Cấu trúc của chất lỏng ion và chất lỏng ion gắn lên silica được phân tích bằng FT-IR, 1H và 13C NMR, TGA-DT, SEM, BET và EDX. Vật liệu được hình thành dựa trên liên kết hydrogen và tương tác van der Waals giữa silica gel và chất lỏng ion. Pha tĩnh này chứng minh là vật liệu chiế pha rắn hiệu quả lưu giữ enrofloxacin, norfloxacin và difloxacin. Cuối cùng, vật liệu được áp dụng trong xử lí mẫu trứng gà và tôm chứa enrofloxacin và difloxacin với hiệu suất thu hồi cao (80-110%).

 


Từ khóa


1-methylpyrolidine; kháng sinh, fluoroquinolone; chất lỏng ion; silica gel; cột chiết pha rắn

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Trích dẫn


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DOI: https://doi.org/10.54607/hcmue.js.19.9.3563(2022)

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