STUDYING MODIFICATION OF STICTIC ACID UNDER AlCl3 CATALYST IN DIMETHYLFORMAMIDE SOLVENT

Tóm tắt

Stictic acid, a depsidone found in many lichen species, is a potentially bioactive compound. Derivatives of stictic acid  were synthesized by halogenation or esterification. However, the effects of these conditions on the decomposition of stictic acid have not yet been studied. Hence, the modification of stictic acid was investigated using an AlCl₃ catalyst and dimethylformamide solvent. The results showed that approximately 20% of the stictic acid yield was transformed into other compounds in these media. The decomposition of stictic acid is due to lactone ring-opening by the AlCl₃ catalyst or the dimethylamine produced by the reaction of AlCl₃ and dimethylformamide.